Duke vs. SMU Dunkel Predictions & Vegas Odds - Jan. 10

The No. 6 Duke Blue Devils (14-1, 3-0 ACC) are 12.5-point favorites for their matchup with the No. 24 SMU Mustangs (12-3, 1-1 ACC) on January 10, 2026, when a pair of the best players in the country -- the Blue Devils' Cameron Boozer and the Mustangs' Kevin Miller -- will be on show at Cameron Indoor Stadium. The point total is 157.5 in the matchup.

Duke took care of business in its last game 84-73 against Louisville on Tuesday. In the victory, Boozer paced Duke with 27 points. SMU is coming off of a 74-70 loss to Clemson in its last outing on Wednesday. Miller scored a team-best 23 points for SMU in the loss.

Duke vs. SMU Odds and Game Time

• When: Saturday, January 10, 2026 at 2 p.m. ET
• Where: Cameron Indoor Stadium in Durham, North Carolina
• Spread favorite: Duke -12.5
• Moneyline favorite: Duke -840
• Moneyline underdog: SMU +565
• Over/Under: 157.5 points

How to watch Duke vs. SMU

• TV Channel: ESPN
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Duke vs. SMU

• Duke and its opponents have hit the over on this game's total (157.5 points) six times this season.
• This season, 12 of SMU's games have ended with a combined score higher than 157.5 points.
• The over/under for the matchup of 157.5 is 19.7 points fewer than the combined points per game averages for the Blue Devils (87.1) and Mustangs (90.1).
• These two teams give up a combined 142.7 points per game, 14.8 points less than this contest's over/under.
• On average, the over/under in Duke's games is 4.4 fewer points than the over/under of 157.5 in this matchup.
• The over/under for this contest is 9.3 points lower than the average over/under in SMU's games this season of 166.8.

Betting the Spread: Duke vs. SMU

• Duke has seven wins against the spread in 15 games this season.
• The Blue Devils have been favored by 12.5 points or more nine times this season and are 3-6 ATS in those contests.
• SMU has played 15 games, with seven wins against the spread.
• Duke has two wins against the spread, and is 7-0 overall, at home this season.
• At home, as a 12.5-point favorite or greater, Duke has two wins ATS (2-4).
• SMU is 1-2 overall, with just one win against the spread, away from home.

Betting the Moneyline: Duke vs. SMU

• This season, Duke has won 11 out of the 12 games, or 91.7%, in which it has been the moneyline favorite.
• The Blue Devils have been at least a -840 moneyline favorite six times this season and won each of those games.
• The bookmakers' moneyline implies a 89.4% chance of a victory for Duke.
• SMU has been chosen as moneyline underdogs in five games this year and has walked away with the win two times (40%) in those games.
• This is the worst odds of a win that sportsbooks have given the Mustangs this season with a +565 moneyline set for this game.
• Oddsmakers have implied with the moneyline set for this matchup that SMU has a 15% chance of pulling out a win.