Duke vs. Clemson Dunkel Predictions & Vegas Odds - Feb. 14

The No. 4 Duke Blue Devils (22-2, 11-1 ACC), winners of nine of their last 10, face the No. 20 Clemson Tigers (20-5, 10-2 ACC), 8-2 in their past 10, on February 14, 2026 at Cameron Indoor Stadium. The Blue Devils are favorites by 12.5 points. The matchup has a point total of 133.5.

In its last time out, Duke won on Tuesday 70-54 against Pittsburgh. Isaiah Evans scored a team-leading 21 points for Duke in the win. Clemson enters this contest on the heels of a 76-66 loss to Virginia Tech on Wednesday. Carter Welling's team-high 19 points paced Clemson in the losing effort.

Duke vs. Clemson Odds and Game Time

• When: Saturday, February 14, 2026 at 12 p.m. ET
• Where: Cameron Indoor Stadium in Durham, North Carolina
• Spread favorite: Duke -12.5
• Moneyline favorite: Duke -840
• Moneyline underdog: Clemson +568
• Over/Under: 133.5 points

How to watch Duke vs. Clemson

• TV Channel: ESPN
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Duke vs. Clemson

• This season, Duke's games have hit the over on this matchup's 133.5-point over/under 17 times.
• This season, 14 of Clemson's games have ended with a combined score higher than 133.5 points.
• Together, the two teams combine for 158.5 points per game, 25.0 points more than the point total of 133.5 for this contest.
• The 128.1 points per game these two teams allow to opponents on average this season are 5.4 fewer than the 133.5 over/under in this contest.
• Duke has a 146.4 average over/under in its games this season, 12.9 more points than the over/under in this matchup.
• Clemson's games have an average over/under of 140.2 points this season, 6.7 more points than the over/under for this matchup.

Betting the Spread: Duke vs. Clemson

• Duke has 12 wins against the spread in 24 games this year.
• The Blue Devils are 5-9 ATS when favored by 12.5 points or more this season.
• In Clemson's 25 games this year, it has 13 wins against the spread.
• Duke is 4-7 against the spread, and 11-0 overall, at home this year.
• As a 12.5-point favorite or greater at home, Duke is 3-6 ATS.
• This year on the road, Clemson is 6-2 against the spread and 6-2 overall.

Betting the Moneyline: Duke vs. Clemson

• Duke has entered the game as moneyline favorites 21 times this season and won 19, or 90.5%, of those games.
• The Blue Devils are undefeated in 12 games this season when favored by -840 or more on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that Duke has a 89.4% chance to win.
• Clemson was defeated in both of the games it has played as moneyline underdogs this season.
• This is the worst odds of a win that sportsbooks have given the Tigers this season with a +568 moneyline set for this game.
• The moneyline set for this matchup implies Clemson has a 15% chance of walking away with the win.