Tigers vs. Brewers Dunkel MLB Picks, Predictions and Prop Bets - April 22

The Detroit Tigers play the Milwaukee Brewers on Wednesday at Comerica Park, at 6:40 p.m. ET. Casey Mize (1-1, 2.78 ERA) gets the start for the Tigers, who are 12-12 this season and third in the AL Central. Chad Patrick (1-0, 0.95 ERA) is the expected starter for the Brewers, who are 13-9 and fourth in the NL Central.

Oddsmakers have made the Tigers a decent moneyline favorite (-136) at home over the Brewers (+115). The contest has an over/under set at 8.

Tigers vs. Brewers Odds, Game Time

• Game day: Wednesday, April 22, 2026
• Game time: 6:40 p.m. ET
• Location: Detroit, Michigan
• Stadium: Comerica Park
• Favorite: Tigers (-136)
• Underdog: Brewers (+115)
• Over/under: 8

How to Watch Tigers vs. Brewers

• TV Channel: DSN and BREW
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Tigers vs. Brewers: Betting the Moneyline

• The Tigers have compiled a 9-6 record in games they were favored on the moneyline (winning 60% of those games).
• Milwaukee has been victorious in five of the nine contests it has been chosen as underdogs in this season.
• Detroit has entered 10 games this season favored by -136 or more and is 5-5 in those contests.
• The Brewers have been listed as an underdog of +115 or more on two occasions this season and lost both games.
• Based on this matchup's moneyline, the Tigers' implied win probability is 57.6%.
• Sportsbooks have implied with the moneyline set for this matchup that the Brewers have a 46.5% chance of pulling out a win.

Tigers vs. Brewers: Betting the Spread & Total

• The Tigers have played in 24 games with an over/under set, and have combined with their opponents to go over the total 11 times (11-12-1).
• Milwaukee and its opponents have gone over the total this season in 13 of its 22 opportunities.
• The Tigers have a 12-12-0 record against the spread this season.
• The Brewers are 14-8-0 against the spread in their 22 games that had a posted line this season.