Tigers vs. Brewers Dunkel MLB Picks, Predictions and Prop Bets - April 21

The Detroit Tigers host the Milwaukee Brewers to open a three-game series at Comerica Park, with first pitch at 6:40 p.m. ET on Tuesday. Keider Montero (1-1, 3.31 ERA) gets the start for the Tigers, who are 12-11 this season and second in the AL Central. Kyle Harrison (1-1, 3.07 ERA) is the expected starter for the Brewers, who are 12-9 and fifth in the NL Central.

The moneyline odds for the Tigers (-114) versus the Brewers (-106) indicate a tight game. The over/under for this contest is set at 8.5.

Tigers vs. Brewers Odds, Game Time

• Game day: Tuesday, April 21, 2026
• Game time: 6:40 p.m. ET
• Location: Detroit, Michigan
• Stadium: Comerica Park
• Favorite: Tigers (-114)
• Underdog: Brewers (-106)
• Over/under: 8.5

How to Watch Tigers vs. Brewers

• TV Channel: DSN and BREW
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Tigers vs. Brewers: Betting the Moneyline

• The Tigers have been the moneyline favorite 14 total times this season. They've finished 9-5 in those games.
• Milwaukee has been pegged as an underdog in eight games this year and has walked away with the win four times (50%) in those games.
• Detroit has a record of 9-5, a 64.3% win rate, when favored by -114 or more by sportsbooks this season.
• This season, the Brewers have been victorious three times in six chances when named as an underdog of at least -106 or longer on the moneyline.
• The Tigers have an implied moneyline win probability of 53.3% in this game.
• The moneyline set for this matchup implies the Brewers have a 51.5% chance of walking away with the win.

Tigers vs. Brewers: Betting the Spread & Total

• The Tigers have combined with opponents to go over the total 10 times this season for a 10-12-1 record against the over/under.
• Games involving Milwaukee have gone over the total set by bookmakers in 12 of 21 chances this season.
• The Tigers have put together a 12-11-0 record ATS this season.
• In 21 games with a line this season, the Brewers have a mark of 13-8-0 against the spread.