DePaul vs. Marquette Dunkel Predictions & Vegas Odds - Jan. 16

The DePaul Blue Demons (10-7, 2-4 Big East) host the Marquette Golden Eagles (6-12, 1-6 Big East) at Wintrust Arena, beginning at 8:30 p.m. ET on Friday, January 16, 2026. The Blue Demons are 4.5-point favorites in the game. The over/under is set at 144.5 for the matchup.

DePaul fell in its last outing 72-60 against UConn on Saturday. Layden Blocker totaled 16 points, five rebounds and two assists for DePaul. Marquette's most recent outing on Tuesday ended in a 92-68 loss to St. John's. Chase Ross scored 20 points in Marquette's loss, leading the team.

DePaul vs. Marquette Odds and Game Time

• When: Friday, January 16, 2026 at 8:30 p.m. ET
• Where: Wintrust Arena in Chicago, Illinois
• Spread favorite: DePaul -4.5
• Moneyline favorite: DePaul -184
• Moneyline underdog: Marquette +152
• Over/Under: 144.5 points

How to watch DePaul vs. Marquette

• TV Channel: FOX Sports 1
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: DePaul vs. Marquette

• Eight of DePaul's games this season have gone over Friday's over/under of 144.5 points.
• There have been 13 Marquette games that finished with a combined score higher than 144.5 points this season.
• Together, the two teams combine for 147.2 points per game, 2.7 points more than the total of 144.5 for this matchup.
• This game's total is 1.3 less than the 145.8 points these two teams combine to give up per game.
• DePaul has seen a 141.5 average over/under in its games this season, three less than the over/under in this contest.
• The over/under for this matchup is seven points lower than the average over/under in Marquette's games this season (151.5 points).

Betting the Spread: DePaul vs. Marquette

• DePaul has played 17 games, with 11 wins against the spread.
• The Blue Demons are 3-4 ATS when favored by 4.5 points or more this season.
• In Marquette's 18 games this year, it has five wins against the spread.
• The Golden Eagles have covered the spread once this year when underdogs by 4.5 points or more (in five chances).
• At home this year, DePaul is 6-5 against the spread and 8-3 overall.
• DePaul is 3-4 ATS as a 4.5-point favorite or more at home.
• Marquette has one win against the spread, and are 0-5 overall, in away games.

Betting the Moneyline: DePaul vs. Marquette

• DePaul has been the moneyline favorite in 10 games this season and won nine (90%) of those contests.
• The Blue Demons have a record of 6-1 in games where oddsmakers favor them by at least -184 on the moneyline.
• The moneyline for this contest implies a 64.8% chance of a victory for DePaul.
• Marquette has been posted as the moneyline underdog eight times this season but has yet walk away from any of those games with an upset.
• The Golden Eagles have yet to win this season when listed as an underdog of +152 or worse on the moneyline this season.
• The moneyline set for this matchup implies Marquette has a 39.7% chance of walking away with the win.

Dunkel Index Prediction for DePaul vs. Marquette

• Pick ATS: DePaul (- 4.5)
• Pick OU: Over (144.5)
  
• Prediction: DePaul 79 - Marquette 72