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Guardians vs. Nationals Dunkel MLB Picks, Predictions and Prop Bets - May 25

25 May 2026 By Data Skrive

The Cleveland Guardians and Washington Nationals square off on Monday at 6:10 p.m. ET, opening a three-game series at Progressive Field. Tanner Bibee (0-6, 3.75 ERA) will start for the Guardians, who are 32-23 this season and first in the AL Central. Zack Littell (3-4, 5.83 ERA) is the expected starter for the Nationals, who are 27-27 and second in the NL East.

The Nationals (+149) are on the road versus the favored Guardians (-178). The game's total is set at 8.

Guardians vs. Nationals Odds, Game Time

  • Game day: Monday, May 25, 2026
  • Game time: 6:10 p.m. ET
  • Location: Cleveland, Ohio
  • Stadium: Progressive Field
  • Favorite: Guardians (-178)
  • Underdog: Nationals (+149)
  • Over/under: 8

How to Watch Guardians vs. Nationals

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Guardians vs. Nationals: Betting the Moneyline

  • The Guardians have been favored on the moneyline 30 total times this season. They've finished 18-12 in those games.
  • Washington has been underdogs in 52 games this season and has come away with the win 26 times (50%) in those contests.
  • Cleveland has not been bigger favorites this season than the -178 moneyline set for this game.
  • This season, the Nationals have come away with a win seven times in 15 chances when named as an underdog of at least +149 or longer on the moneyline.
  • The Guardians have an implied moneyline win probability of 64% in this matchup.
  • The Nationals have an implied victory probability of 40.2% according to the moneyline set by sportsbooks for this matchup.

Guardians vs. Nationals: Betting the Spread & Total

  • The Guardians have combined with opponents to go over the total 26 times this season for a 26-29-0 record against the over/under.
  • Washington's games have gone over the total in 33 of its 54 chances.
  • The Guardians have covered 56.4% of their games this season, going 31-24-0 ATS.
  • The Nationals have posted a record of 34-20-0 against the spread this season.
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