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Guardians vs. Angels Dunkel MLB Picks, Predictions and Prop Bets - May 13

13 May 2026 By Data Skrive

The Cleveland Guardians hope to sweep a three-game series versus the Los Angeles Angels, at 1:10 p.m. ET on Wednesday. Parker Messick (4-1, 2.30 ERA) gets the start for the Guardians, who are 23-21 this season and first in the AL Central. Reid Detmers (1-3, 4.33 ERA) is expected to start for the Angels, who are 16-27 and fourth in the AL West.

The Angels (+134) take their show on the road to face the favored Guardians (-160). The over/under for the Guardians-Angels game is 7.

Guardians vs. Angels Odds, Game Time

  • Game day: Wednesday, May 13, 2026
  • Game time: 1:10 p.m. ET
  • Location: Cleveland, Ohio
  • Stadium: Progressive Field
  • Favorite: Guardians (-160)
  • Underdog: Angels (+134)
  • Over/under: 7

How to Watch Guardians vs. Angels

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Guardians vs. Angels: Betting the Moneyline

  • The Guardians have won 52.2% of the games this season when they were the moneyline favorite (12-11).
  • Los Angeles has been victorious in 12, or 35.3%, of the 34 contests it has been chosen as underdogs in this season.
  • Cleveland has entered three games this season favored by -160 or more and is 1-2 in those contests.
  • This season, the Angels have come away with a win eight times in 17 chances when named as an underdog of at least +134 or worse on the moneyline.
  • Based on this game's moneyline, the Guardians have an implied win probability of 61.5%.
  • Oddsmakers have implied with the moneyline set for this matchup that the Angels have a 42.7% chance of pulling out a win.

Guardians vs. Angels: Betting the Spread & Total

  • In the 44 games in which bookmakers have set an over/under for the Guardians, they have combined with opponents to go over the total 22 times (22-22-0).
  • Los Angeles and its opponents have hit the over in 20 of its 43 games with a total this season.
  • The Guardians have a 24-20-0 record against the spread this season (covering 54.5% of the time).
  • The Angels are 21-22-0 against the spread in their 43 games with a line set by sportsbooks this season.
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