Reds vs. Rays Dunkel MLB Picks, Predictions and Prop Bets - April 21

The Cincinnati Reds will look to keep a four-game win streak alive when they visit the Tampa Bay Rays at 6:40 p.m. ET on Tuesday. Chase Burns (1-1, 2.42 ERA) will start for the Reds, who are 15-8 this season and first in the NL Central. Steven Matz (3-0, 3.80 ERA) is starting for the Rays, who are 12-10 and second in the AL East.

Oddsmakers expect a close matchup between the Reds (-112 to win) and the Rays (-107). The over/under in this contest is 7.5.

Reds vs. Rays Odds, Game Time

• Game day: Tuesday, April 21, 2026
• Game time: 6:40 p.m. ET
• Location: St. Petersburg, Florida
• Stadium: Tropicana Field
• Favorite: Reds (-112)
• Underdog: Rays (-107)
• Over/under: 7.5

How to Watch Reds vs. Rays

• TV Channel: RAYS and CINR
• Live Stream: Fubo (Watch for free)

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Reds vs. Rays: Betting the Moneyline

• The Reds have won three of the five games they were listed as the moneyline favorite this season (60%).
• Tampa Bay has been underdogs in 11 games this season and has come away with the win six times (54.5%) in those contests.
• Cincinnati is 2-2 this season when entering a game favored by -112 or more on the moneyline.
• This season, the Rays have been victorious five times in nine chances when named as an underdog of at least -107 or longer on the moneyline.
• Based on this contest's moneyline, the Reds have an implied win probability of 52.8%.
• The Rays have an implied victory probability of 51.7% according to the moneyline set by oddsmakers for this matchup.

Reds vs. Rays: Betting the Spread & Total

• The Reds have had an over/under set by oddsmakers 23 times, and have combined with opponents to go over the total in 12 of those games (12-10-1).
• So far this season, Tampa Bay and its opponents have hit the over in 14 of its 22 games with a total.
• The Reds have put together a 15-8-0 record ATS this season (covering 65.2% of the time).
• The Rays have an against the spread record of 12-10-0 in 22 games with a line this season.