White Sox vs. Astros Dunkel MLB Picks, Predictions and Prop Bets - July 25

The Houston Astros aim to add on to their four-game winning streak when they take on the Chicago White Sox on Saturday at 7:10 p.m. ET, at Rate Field. Sean Burke (7-4, 3.20 ERA) will start for the White Sox, who are 54-48 this season and first in the AL Central. Hunter Brown (1-1, 4.05 ERA) is expected to start for the Astros, who are 51-54 and third in the AL West.

Bookmakers have made the White Sox a decent moneyline favorite (-125) at home over the Astros (+104). The game has an over/under set at 8.5 runs.

White Sox vs. Astros Odds, Game Time

• Game day: Saturday, July 25, 2026
• Game time: 7:10 p.m. ET
• Location: Chicago, Illinois
• Stadium: Rate Field
• Favorite: White Sox (-125)
• Underdog: Astros (+104)
• Over/under: 8.5

How to Watch White Sox vs. Astros

• TV Channel: CHSN and SCHN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

White Sox vs. Astros: Betting the Moneyline

• The White Sox have won 14 of the 22 games they were favored on the moneyline this season (63.6%).
• Houston has come away with 33 wins in the 64 contests it has been listed as the underdogs in this season.
• Chicago has a record of 7-4, a 63.6% win rate, when favored by -125 or more by oddsmakers this season.
• This season, the Astros have been victorious 23 times in 45 chances when named as an underdog of at least +104 or worse on the moneyline.
• The White Sox have an implied moneyline win probability of 55.6% in this contest.
• The Astros have an implied victory probability of 49% according to the moneyline set for this matchup.

White Sox vs. Astros: Betting the Spread & Total

• The White Sox have played in 102 games with set over/under, and have combined with opponents to go over the total 59 times (59-42-1).
• Houston and its opponents have gone over the total this season in 54 of its 105 opportunities.
• The White Sox have covered 58.8% of their games this season, going 60-42-0 against the spread.
• The Astros are 53-52-0 against the spread in their 105 games with a line set by sportsbooks this season.