Cubs vs. Giants Dunkel MLB Picks, Predictions and Prop Bets - June 6

Casey Schmitt leads the San Francisco Giants into a matchup versus the Chicago Cubs, after homering twice in an 18-3 victory over the Cubs, at 2:20 p.m. ET on Saturday. Ben Brown (2-2, 1.92 ERA) will start for the Cubs, who are 33-31 this season and fourth in the NL Central. Landen Roupp (5-6, 4.22 ERA) is the expected starter for the Giants, who are 26-38 and fourth in the NL West.

The Giants (+133) are on the road versus the favored Cubs (-157). The game has an over/under of 7.5 runs.

Cubs vs. Giants Odds, Game Time

• Game day: Saturday, June 6, 2026
• Game time: 2:20 p.m. ET
• Location: Chicago, Illinois
• Stadium: Wrigley Field
• Favorite: Cubs (-157)
• Underdog: Giants (+133)
• Over/under: 7.5

How to Watch Cubs vs. Giants

• TV Channel: MARQ and NBCS-BA
• Live Stream: Fubo (Watch Now!)

Bet now on FanDuel Sportsbook!

Cubs vs. Giants: Betting the Moneyline

• The Cubs have been the moneyline favorite 44 total times this season. They've finished 23-21 in those games.
• San Francisco has been pegged as an underdog in 42 games this year and has walked away with the win 16 times (38.1%) in those games.
• Chicago has a record of 10-5 in games when oddsmakers favor them by at least -157 on the moneyline.
• This season, the Giants have come away with a win six times in 11 chances when named as an underdog of at least +133 or worse on the moneyline.
• The Cubs have a 61.1% chance to win this game based on the moneyline's implied probability.
• Oddsmakers have implied with the moneyline set for this matchup that the Giants have a 42.9% chance of pulling out a win.

Cubs vs. Giants: Betting the Spread & Total

• The Cubs have played in 64 games with a set over/under, and have combined with their opponents to go over the total 36 times (36-26-2).
• San Francisco and its opponents have gone over the total this season in 33 of its 64 opportunities.
• The Cubs have gone 24-40-0 against the spread this season.
• The Giants have an against the spread record of 27-37-0 in 64 games with a line this season.