Bills vs. Texans Week 1 Dunkel NFL Picks, Predictions and Odds

The Buffalo Bills (0-0) are favored by 1.5 points versus the Houston Texans (0-0) on September 13, 2026, starting at 1 p.m. ET, airing on CBS. The expected point total for the matchup is set at 44.5.

The Bills ranked seventh in total defense last season (293.1 yards allowed per game), but they played really well on the other side of the ball, ranking fourth-best in the NFL with 376.3 total yards per game. The Texans ranked 18th in total offense this year (327 yards per game), but they really clicked on defense, ranking first in the NFL with 277.2 yards allowed per game.

Bills vs. Texans Odds and Game Time

• Date: Sunday, September 13, 2026
• Time: 1 p.m. ET
• City: Houston, Texas
• Venue: NRG Stadium
• Total: 44.5 points
• Spread: Bills -1.5
• Moneyline: Bills (-112), Texans (-108)

How to watch Bills vs. Texans

• TV Channel: CBS

Betting the Over/Under: Bills vs. Texans

• The Bills and their opponents scored more than 44.5 points in eight of 17 games last season.
• A total of nine of the Bills' games last season hit the over.
• The Texans and their opponents combined to score more than 44.5 points in five of 17 games last season.
• In Houston games last season, combined scoring went over the point total six times.
• These teams scored a combined 52.1 points per game last season, 7.6 more points than this matchup's point total.
• Opponents of these teams combined to average 38.9 points per game last year, 5.6 fewer points than this contest's total.

Betting the Spread: Bills vs. Texans

• Buffalo went 8-9-0 ATS last season.
• When playing as at least 1.5-point favorites last season, Buffalo had an ATS record of 6-9.
• The Texans covered nine times in 17 games with a spread last season.
• When playing as at least 1.5-point underdogs last season, Houston had an ATS record of 5-3.
• The Texans were 5-4 against the spread, and 7-2 overall, at home last year.
• At home last season, as 1.5-point underdogs or greater, Houston was unbeaten ATS (2-0).
• The Bills were 4-4 against the spread, and 5-3 overall, in away games last season.
• Buffalo went 4-4 ATS as 1.5-point favorites or more away from home.

Betting the Moneyline: Bills vs. Texans

• Buffalo won 10 of the 15 games it was favored on the moneyline last season (66.7%).
• Last season, the Texans won five out of the eight games in which they were the underdog.
• When it played as a moneyline favorite with odds of -112 or shorter, Buffalo went 10-5 (66.7%).
• Houston had a record of 5-3 when it was set as an underdog of -108 or more by oddsmakers last season.
• The Bills have a 52.8% chance to win this game based on the moneyline's implied probability.

Dunkel Prediction for Bills vs. Texans

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