Bills vs. Texans Week 1 Dunkel NFL Picks, Predictions and Odds

The Buffalo Bills (0-0) are favored by 1.5 points against the Houston Texans (0-0) on September 13, 2026, starting at 1 p.m. ET, airing on CBS. The predicted point total for the game is 45.5.

The Bills owned the seventh-ranked defense last season (293.1 yards allowed per game), and they were better on the other side of the ball, ranking fourth-best with 376.3 yards per game. The Texans ranked 13th in points scored last season (23.8 points per game), but they thrived on the other side of the ball, ranking second-best in the NFL with 17.4 points allowed per game.

Bills vs. Texans Odds and Game Time

• Date: Sunday, September 13, 2026
• Time: 1 p.m. ET
• City: Houston, Texas
• Venue: NRG Stadium
• Total: 45.5 points
• Spread: Bills -1.5
• Moneyline: Bills (-118), Texans (-102)

How to watch Bills vs. Texans

• TV Channel: CBS

Betting the Over/Under: Bills vs. Texans

• The Bills and their opponents went over 45.5 combined points in eight of 17 games last season.
• A total of nine of the Bills' games last season hit the over.
• Houston played five games last season that ended with a combined score higher than 45.5 points.
• In Houston games last year, combined scoring went over the point total six times.
• These two teams averaged a combined 52.1 points per game last season, 6.6 more points than this matchup's total.
• These two teams gave up a combined 38.9 points per game last year, 6.6 fewer points than the over/under for this contest.

Betting the Spread: Bills vs. Texans

• Buffalo compiled an 8-9-0 ATS record last year.
• When playing as at least 1.5-point favorites last season, Buffalo had an ATS record of 6-9.
• The Texans went 9-8-0 ATS last season.
• Houston covered the spread five times last season (5-3 ATS) when playing as at least 1.5-point underdogs.
• The Texans were 7-2 overall, and 5-4 against the spread, at home last year.
• At home last season, as 1.5-point underdogs or greater, Houston was unbeaten ATS (2-0).
• The Bills were 4-4 against the spread, and 5-3 overall, in away games last season.
• Last season Buffalo went 4-4 ATS as 1.5-point favorites or more on the road.

Betting the Moneyline: Bills vs. Texans

• Buffalo won 66.7% of the games last season when it was favored on the moneyline (10-5).
• The Texans were underdogs eight times last season and won five of those games.
• Buffalo had a 10-5 record last year (winning 66.7% of its games) when playing as a moneyline favorite of -118 or shorter.
• Houston had a record of 3-3 when it was set as an underdog of -102 or more by sportsbooks last season.
• The implied moneyline probability in this matchup gives the Bills a 54.1% chance to win.

Dunkel Prediction for Bills vs. Texans

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