Boston University vs. Lafayette Dunkel Predictions & Vegas Odds - Jan. 21

The Boston University Terriers (7-12, 2-4 Patriot League) host the Lafayette Leopards (5-14, 2-4 Patriot League) at Case Gym, beginning at 6 p.m. ET on Wednesday, January 21, 2026. The Leopards are 4.5-point underdogs in the game. The matchup has a point total of 146.5.

Boston University dropped its most recent outing 74-57 against Loyola (MD) on Saturday. Ben Defty totaled 18 points, 10 rebounds and zero assists for Boston University. In its last game on Saturday, Lafayette secured a 74-55 victory against Holy Cross. Andrew Phillips totaled 19 points, one rebound and three assists for Lafayette.

Boston University vs. Lafayette Odds and Game Time

• When: Wednesday, January 21, 2026 at 6 p.m. ET
• Where: Case Gym in Boston, Massachusetts
• Spread favorite: Boston University -4.5
• Moneyline favorite: Boston University -197
• Moneyline underdog: Lafayette +163
• Over/Under: 146.5 points

How to watch Boston University vs. Lafayette

• TV Channel: ESPN+
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Boston University vs. Lafayette

• This season, Boston University and its opponents have combined to outscore Wednesday's total of 146.5 points 11 times.
• This season, nine games Lafayette has played finished with a combined score higher than 146.5 points.
• The Terriers average 75.8 points per game against the Leopards' 69.9, amounting to 0.8 points under the matchup's point total of 146.5.
• The 152.3 points per game these two teams allow their opponents to score on average this season are 5.8 more than the 146.5 total in this contest.
• On average, Boston University has seen a 152.4-point over/under in its games this season, 5.9 more points than the over/under in this contest.
• Lafayette's games have an average over/under of 145.7 points this season, 0.8 points lower than the over/under for this matchup.

Betting the Spread: Boston University vs. Lafayette

• Boston University has seven wins against the spread in 18 games this year.
• This season, the Terriers have just one ATS win in four games as a favorite of 4.5 points or more.
• Lafayette has played 18 games, with eight wins against the spread.
• The Leopards have an ATS record of 4-5 in their nine games as an underdog of 4.5 points or more this year.
• Boston University is 3-4 overall, and 3-4 against the spread, at home.
• Boston University has one win ATS (1-2) as a 4.5-point favorite or more at home.
• On the road, Lafayette is 1-9 overall and 5-5 against the spread.

Betting the Moneyline: Boston University vs. Lafayette

• This season, Boston University has won four out of the 10 games in which it has been the moneyline favorite.
• The Terriers are 1-3 this season when entering a game favored by -197 or more on the moneyline.
• Boston University has a 66.3% chance to win this game based on the implied probability of the moneyline.
• Lafayette has been victorious in one, or 7.7%, of the 13 contests it has been chosen as a moneyline underdog in this season.
• The Leopards have won all of their nine games in which they were named as at least a +163 moneyline underdog.
• Lafayette has an implied victory probability of 38% according to the moneyline set for this matchup.