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Red Sox vs. Orioles Dunkel MLB Picks, Predictions and Prop Bets - July 22

21 July 2026 By Data Skrive

The Boston Red Sox aim to continue their 14-game winning streak when they take on the Baltimore Orioles on Wednesday at 1:35 p.m. ET, at Fenway Park. Jake Bennett (5-3, 2.35 ERA) gets the start for the Red Sox, who are 51-48 this season and third in the AL East. Dean Kremer (1-2, 4.15 ERA) is the expected starter for the Orioles, who are 49-52 and fourth in the AL East.

The Red Sox (-151) are moneyline favorites at home over the Orioles (+124). The game's total is 9.5.

Red Sox vs. Orioles Odds, Game Time

  • Game day: Wednesday, July 22, 2026
  • Game time: 1:35 p.m. ET
  • Location: Boston, Massachusetts
  • Stadium: Fenway Park
  • Favorite: Red Sox (-151)
  • Underdog: Orioles (+124)
  • Over/under: 9.5

How to Watch Red Sox vs. Orioles

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Red Sox vs. Orioles: Betting the Moneyline

  • The Red Sox have been the moneyline favorite 63 total times this season. They've gone 32-31 in those games.
  • Baltimore has been underdogs in 49 games this season and has come away with the win 22 times (44.9%) in those contests.
  • Boston is 8-8 this season when entering a game favored by -151 or more on the moneyline.
  • This season, the Orioles have been victorious four times in 12 chances when named as an underdog of at least +124 or longer on the moneyline.
  • Based on this matchup's moneyline, the Red Sox's implied win probability is 60.2%.
  • The moneyline set for this matchup implies the Orioles have a 44.6% chance of coming away with a victory in the contest.

Red Sox vs. Orioles: Betting the Spread & Total

  • The Red Sox have combined with opponents to go over the total 44 times this season for a 44-50-5 record against the over/under.
  • Baltimore's games have gone over the total in 54 of its 101 chances.
  • The Red Sox have put together a 48-51-0 record ATS this season (covering 48.5% of the time).
  • The Orioles have posted a record of 51-50-0 against the spread this season.
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