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Orioles vs. Guardians Dunkel MLB Picks, Predictions and Prop Bets - Sept. 8

08 September 2026 By Data Skrive

The Baltimore Orioles square off against the Cleveland Guardians after Coby Mayo homered twice in a 6-4 victory over the Guardians. The game starts at 6:35 p.m. ET on Tuesday. Brandon Young (9-3, 3.42 ERA) gets the start for the Orioles, who are 70-75 this season and fifth in the AL East. Tanner Bibee (5-15, 4.06 ERA) is starting for the Guardians, who are 73-72 and second in the AL Central.

The Orioles are moderate favorites on the moneyline (-125) at home over the Guardians (+101). The total in this contest is set at 8.5.

Orioles vs. Guardians Odds, Game Time

  • Game day: Tuesday, September 8, 2026
  • Game time: 6:35 p.m. ET
  • Location: Baltimore, Maryland
  • Stadium: Oriole Park at Camden Yards
  • Favorite: Orioles (-125)
  • Underdog: Guardians (+101)
  • Over/under: 8.5

How to Watch Orioles vs. Guardians

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Orioles vs. Guardians: Betting the Moneyline

  • The Orioles have won 36 of the 67 games they were the moneyline favorite this season (53.7%).
  • Cleveland has been pegged as an underdog in 55 games this year and has walked away with the win 26 times (47.3%) in those games.
  • Baltimore has entered 49 games this season favored by -125 or more and is 26-23 in those contests.
  • The Guardians have a win-loss record of 25-22 when favored by +101 or worse by bookmakers this year.
  • The Orioles have an implied moneyline win probability of 55.6% in this game.
  • The Guardians have an implied victory probability of 49.8% according to the moneyline set for this matchup.

Orioles vs. Guardians: Betting the Spread & Total

  • The Orioles have played in 145 games with over/under set, and have combined with opponents to go over the total 72 times (72-70-3).
  • Games involving Cleveland have gone over the total set by sportsbooks in 68 of 145 chances this season.
  • The Orioles have collected a 74-71-0 record against the spread this season (covering 51% of the time).
  • The Guardians have posted a record of 68-77-0 against the spread this season.
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