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Athletics vs. Astros Dunkel MLB Picks, Predictions and Prop Bets - Sept. 23

23 September 2025 By Data Skrive

The Athletics and Houston Astros clash on Tuesday at 10:05 p.m. ET, opening a three-game series at Sutter Health Park. Jeffrey Springs (10-11, 4.17 ERA) will start for the Athletics, who are 73-83 this season and fourth in the AL West. Cristian Javier (2-3, 4.45 ERA) is starting for the Astros, who are 84-72 and second in the AL West.

With moneyline odds of -110 for the Athletics and -110 for the Astros, this could be a close contest. The contest has an over/under set at 10.5.

Athletics vs. Astros Odds, Game Time

  • Game day: Tuesday, September 23, 2025
  • Game time: 10:05 p.m. ET
  • Location: West Sacramento, California
  • Stadium: Sutter Health Park
  • Favorite: Athletics (-110)
  • Underdog: Astros (-110)
  • Over/under: 10.5

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Athletics vs. Astros: Betting the Moneyline

  • The Athletics have won 17 of the 38 games they were listed as the moneyline favorite this season (44.7%).
  • The Astros have won in 32, or 57.1%, of the 56 contests they have been named as odds-on underdogs in this year.
  • This season, the Athletics have won 18 of their 39 games, or 46.2%, when favored by at least -110 on the moneyline.
  • This season, the Astros have come away with a win 32 times in 56 chances when named as an underdog of at least -110 or worse on the moneyline.
  • Based on this contest's moneyline, the Athletics' implied win probability is 52.4%.
  • The moneyline set for this matchup implies the Astros have a 52.4% chance of coming away with a victory in the contest.

Athletics vs. Astros: Betting the Spread & Total

  • The Athletics have played in 156 games with an over/under set, and have combined with their opponents to go over the total 74 times (74-72-10).
  • Games involving the Astros have gone over the total set by bookmakers in 71 of 156 chances this season.
  • The Athletics have collected an 82-74-0 record against the spread this season (covering 52.6% of the time).
  • The Astros have posted a record of 78-78-0 against the spread this season.

Dunkel Index Prediction for Athletics vs. Astros

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