Athletics vs. Astros Dunkel MLB Picks, Predictions and Prop Bets - June 5

The Athletics and Houston Astros square off on Friday at 8:10 p.m. ET, opening a three-game series at Daikin Park. Jack Perkins (2-2, 5.46 ERA) gets the start for the Athletics, who are 30-32 this season and second in the AL West. Peter Lambert (4-4, 3.77 ERA) is starting for the Astros, who are 28-36 and fourth in the AL West.

Bookmakers expect a close matchup between the Athletics (-110 to win) and the Astros (-109). The game has an over/under of 9 runs.

Athletics vs. Astros Odds, Game Time

• Game day: Friday, June 5, 2026
• Game time: 8:10 p.m. ET
• Location: Houston, Texas
• Stadium: Daikin Park
• Favorite: Athletics (-110)
• Underdog: Astros (-109)
• Over/under: 9

How to Watch Athletics vs. Astros

• TV Channel: SCHN and NBCS-CA
• Live Stream: Fubo (Watch Now!)

Bet now on FanDuel Sportsbook!

Athletics vs. Astros: Betting the Moneyline

• The Athletics have compiled a 7-11 record in games they were favored on the moneyline (winning 38.9% of those games).
• The Astros have been chosen as underdogs in 46 games this year and have walked away with the win 23 times (50%) in those games.
• This season, the Athletics have won seven of their 18 games, or 38.9%, when favored by at least -110 on the moneyline.
• This year, the Astros have won 23 of 46 games when listed as at least -109 or better on the moneyline.
• Based on this contest's moneyline, the Athletics' implied win probability is 52.4%.
• The moneyline set for this matchup implies the Astros have a 52.2% chance of coming away with a victory in the contest.

Athletics vs. Astros: Betting the Spread & Total

• The Athletics have combined with their opponents to go over the total 31 times this season for a 31-29-2 record against the over/under.
• Games involving the Astros have gone over the total set by bookmakers in 35 of 64 chances this season.
• The Athletics are 32-30-0 ATS this season.
• The Astros are 29-35-0 against the spread in their 64 games with a line set by sportsbooks this season.