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Arizona Cardinals at San Francisco 49ers Betting Preview

04 November 2021

The NFC West Division is loaded with some terrific teams, and two of them will square off on Sunday in Week 9. The San Francisco 49ers host the Arizona Cardinals, and the home team will be looking to get back in the division race.

Arizona started off the season by winning their first seven games, but the winning streak ended with a Week 8 loss to the Green Bay Packers. The Cardinals are still one of the top teams in the NFL, and they are also a perfect 4-0 away from home this season.

San Francisco was able to snap a four-game losing streak with a victory over the Chicago Bears in Week 8. The 49ers are still just 3-4 on the year, and they are in danger of falling out of the NFC West Division race.

The Arizona Cardinals are 2.5-point favorites over the San Francisco 49ers in this NFC West showdown.

Cardinals Can Really Score

Arizona comes into Week 9, scoring nearly 31 points per game this season, and they are able to attack teams in a variety of ways. The Cardinals are averaging 284 passing yards per game, but they can also rack up yards on the ground.

Quarterback Kyler Murray has been a superstar this season as he has thrown for more than 2,200 yards while also making plays with his legs. Murray has thrown seven interceptions through eight weeks, and he will need to limit his mistakes.

The defense of the Cardinals has been the biggest surprise as they are allowing just 17 points per game. Arizona is able to get after opposing quarterbacks, and that aggressiveness has paid off this season.

Defense Needed For Niners

If the 49ers are going to win this game, then it will have to get it done on the defensive side of the football. San Francisco is allowing over 24 points per game, and that could be a recipe for disaster on Sunday afternoon.

Quarterback Jimmy Garoppolo had a pair of rushing touchdowns in the Week 8 win, and he continues to make winning plays for San Francisco. The 49ers aren't going to be an explosive offensive team, but they have some talented pieces.

San Francisco will need to find a way to slow down the pace if they plan on picking up a win over the explosive Cardinals.

Cardinals Dominant Division Rival

San Francisco looked sharp in the Week 8 win over the Chicago Bears, but there are still a number of glaring issues with this team. The 49ers' defense has been a disaster all season long, and that's not going to bode well against the explosive Cardinals.

Kyler Murray has been playing lights out for the Cardinals, and he is going to get back on track in this game. Arizona simply has too many weapons for San Francisco, and it's going to be hard for the 49ers to keep this game close.

Bet the Arizona Cardinals -2.5 as they head into San Francisco and pick up a double-digit win over the San Francisco 49ers.

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