Ohio State vs. UCLA Dunkel NCAA Football Picks, Predictions and Odds - Nov. 15

The No. 1 Ohio State Buckeyes (9-0) are 31.5-point favorites when they host the UCLA Bruins (3-6) in a Big Ten matchup on Saturday, November 15, 2025 at Ohio Stadium.

The Buckeyes' most recent contest was against the Purdue Boilermakers, and they won by a score of 34-10.

The Bruins' last contest was against the Nebraska Cornhuskers, and they lost by a score of 28-21.

Ohio State vs. UCLA Predictions

For the upcoming game between the Ohio State Buckeyes and UCLA Bruins, computer-calculated against-the-spread, over/under, and score predictions are below, based on data from Dunkel Index.

• Pick ATS: Buckeyes (- 31.5)
• Pick OU: Over (47.5)
  
• Prediction: Buckeyes 47 - Bruins 10

Bet now on FanDuel Sportsbook!

Ohio State vs. UCLA Moneylines

Take a peek below at the most recent moneylines for the Buckeyes-Bruins game.

• Ohio State Moneyline: -9091
• UCLA Moneyline: +2075

Pick with the best in the business! Get free picks for every game, every week at the Dunkel Index.

Ohio State Betting Insights

• Ohio State has been listed as the moneyline favorite a total of eight times this season, and it has won all of those games.
• Ohio State has not yet played as a moneyline favorite of -9091 or shorter.
• The Buckeyes and their opponents have combined to score more than 47.5 points in three of nine games this season.
• The Buckeyes have an average total of 49.2 in their games this year, 1.7 more points than this matchup's over/under.
• The Buckeyes are the 19th-highest scoring team in college football this year. The Bruins have scored the 119th-most points.

UCLA Betting Insights

• UCLA has won two of the five games it has played as an underdog this season.
• UCLA has not entered a game this season as a bigger underdog on the moneyline than the +2075 odds on them winning this game.
• UCLA games this season have had a combined scoring total higher than 47.5 points in six of nine outings.
• UCLA's games this year have had a 50.4-point total on average, 2.9 more points than this matchup's over/under.

Watch Ohio State vs. UCLA on Fubo.

Key Stats for Ohio State vs. UCLA

• The Buckeyes have been making things happen on both sides of the ball this season, as they rank 25th-best in total offense (441.4 yards per game) and best in total defense (211.6 yards allowed per game).
• Ohio State has been surging on both offense and defense, ranking 18th-best in scoring offense (36.3 points per game) and best in scoring defense (7.2 points allowed per game).
• In terms of total yards, the Bruins rank 104th in the FBS (344.6 total yards per game) and 77th on defense (376.7 total yards allowed per contest).
• UCLA has lots of room to get better, as it ranks 21st-worst in points per game (20.4) this season and 25th-worst in points surrendered per game (30.7).