Northwestern vs. DePaul Dunkel Predictions & Vegas Odds - Nov. 14

The Northwestern Wildcats (3-0) visit the DePaul Blue Demons (2-1) at Wintrust Arena, tipping off at 8:30 p.m. ET on Friday, November 14, 2025. The Blue Demons are 6.5-point underdogs in the game. The matchup has an over/under of 138.5.

Last time out, Northwestern won on Monday 110-63 against Cleveland State. In Northwestern's win, Nick Martinelli led the way with a team-high 21 points (adding seven rebounds and one assist). DePaul's last game on Tuesday ended in a 66-53 loss to Buffalo. N.J. Benson recorded 11 points, eight rebounds and one assist for DePaul.

Northwestern vs. DePaul Odds and Game Time

• When: Friday, November 14, 2025 at 8:30 p.m. ET
• Where: Wintrust Arena in Chicago, Illinois
• Spread favorite: Northwestern -6.5
• Moneyline favorite: Northwestern -308
• Moneyline underdog: DePaul +250
• Over/Under: 138.5 points

How to watch Northwestern vs. DePaul

• TV Channel: truTV
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Northwestern vs. DePaul

• Northwestern played 19 games with over 138.5 points scored, its current matchup's total, last season.
• DePaul's games went over 138.5 total points scored in 26 of 34 matchups last year.
• The Wildcats and the Blue Demons combined to average 6.3 more points per game a season ago than the total of 138.5 set for this matchup.
• Opponents of the two teams averaged a combined 5.2 more points per game last season (143.7) than this matchup's over/under of 138.5 points.
• Northwestern's average point total in matchups last year was 141.6, 3.1 points higher than the total in this game.
• The average total in DePaul's games in 2024 was 8.4 more points than the point total of 138.5 in this outing.

Betting the Spread: Northwestern vs. DePaul

• Northwestern went 17-15-1 ATS last season.
• The Wildcats had an ATS record of 4-4-1 when playing as at least 6.5-point favorites last season.
• DePaul went 17-17-0 ATS last year.
• The Blue Demons were an underdog by 6.5 points or more 17 times last season, and covered the spread in seven of those contests.
• At home last year, DePaul was 11-8 overall and 10-9 against the spread.
• At home last season, DePaul was 5-2 ATS as a 6.5-point underdog or greater.
• Away from home last season, Northwestern was 2-9 overall and 6-5 against the spread.

Betting the Moneyline: Northwestern vs. DePaul

• Northwestern was favored on the moneyline 15 total times last season. It went 13-2 in those games.
• The Wildcats had a 6-1 record last year (winning 85.7% of their games) when they played as a moneyline favorite of -308 or shorter.
• Northwestern has an implied moneyline win probability of 75.5% in this contest.
• Last season, DePaul won four out of the 23 games, or 17.4%, in which it was the underdog.
• The Blue Demons had a record of 2-12 in games where bookmakers had them as underdogs of at least +250 on the moneyline.
• DePaul has a 28.6% chance to win this game based on the implied probability of the moneyline.