Missouri vs. Mississippi State Dunkel NCAA Football Picks, Predictions and Odds - Nov. 15

The Missouri Tigers (6-3) host the Mississippi State Bulldogs (5-5) on Saturday, November 15, 2025 in a matchup between SEC foes at Memorial Stadium/Faurot Field. Mississippi State is a touchdown underdog.

The Tigers lost versus the Texas A&M Aggies in their most recent game, 38-17.

Last time out, the Bulldogs fell to the Georgia Bulldogs, with 41-21 being the final score.

Missouri vs. Mississippi State Predictions

For the upcoming game between the Missouri Tigers and Mississippi State Bulldogs, computer-derived against-the-spread, over/under, and score predictions are below, per Dunkel Index.

• Pick ATS: Tigers (- 7)
• Pick OU: Under (51.5)
  
• Prediction: Tigers 28 - Bulldogs 17

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Missouri vs. Mississippi State Moneylines

Grab a look below at the most up-to-date moneylines for the Tigers-Bulldogs game.

• Missouri Moneyline: -276
• Mississippi State Moneyline: +222

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Missouri Betting Insights

• Missouri has won all five of the games it has been listed as the moneyline favorite this season.
• Missouri has won all three games it has played as a moneyline favorite with odds of -276 or shorter.
• The Tigers and their opponents have gone over 51.5 combined points in four of nine games this season.
• The average point total in Tigers games this season is 50.4, 1.1 points fewer than this matchup's over/under.
• The Tigers score the 36th-most points in college football this season, while the Bulldogs' offense puts up the 23rd-most.

Mississippi State Betting Insights

• Mississippi State has entered the game as an underdog seven times this season and won twice.
• This season, Mississippi State has been at least a +222 underdog on the moneyline five times, losing each of those contests.
• Mississippi State has combined with its opponent to score more than 51.5 points in five of 10 games this season.
• Mississippi State's games this year have had a 56.5-point total on average, 5.0 more points than this matchup's over/under.

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Key Stats for Missouri vs. Mississippi State

• The Tigers have been clicking on all fronts this season, as they rank 21st-best in total offense (452.3 yards per game) and eighth-best in total defense (266.9 yards allowed per game).
• Missouri has the 30th-ranked offense this season (33.3 points per game), and has been more effective defensively, ranking 21st-best with only 19.1 points allowed per game.
• The Bulldogs rank 61st with 399.6 total yards per contest on offense, and they rank 91st with 388.7 total yards allowed per game on the defensive side of the ball.
• In terms of points scored Mississippi State ranks 47th in the FBS (32.0 points per game), and it is 85th defensively (26.3 points allowed per contest).